2024


  • New video interview: ‘My Lab in 3 Minutes’ video by the CRUK Cambridge Centre’s Fundamental Biology of Cancer (FBC) Programme on our lab’s research on pancreatic cancer and how tumour stiffness influences cell behaviour.

Sep 2024


  • ‘Scar/WAVE drives actin protrusions independently of its VCA domain using proline-rich domains’: New publication in Current Biology, a collaboration between Insall and Machesky lab groups providing novel insights into Scar/Wave Regulatory Complex Mechanistic Function. Read more…

Sep 2024


July 2024


  • Aspiring Students Training Programme (ASTP): it was a pleasure to be part of the ASTP programme for the first year running in the Department of Biochemistry. Thank you to Dr. Sayantika Ghosh for supervising the week-long visit of our A-level student!

July 2024


  • 2024 Alkis Memorial Fund Prize: Congratulations to Part II student, Yuexuan Zhang, on winning the prize for the highest project mark in her cohort following some fantastic work in the Machesky Lab on the therapeutic potential of Src inhibitors in pancreatic cancer, supervised by Dr. Lisa Dobson. 

July 2024


  • ‘Soft glassy rheology of single cells with pathogenic protein aggregates’: Congratulations to Machesky Lab Post-Doc Dr. Shatruhan Rajput on his recent publication on the effect of protein aggregates on actin-dependent cell mechanics. Read more…

July 2024


  • ‘CD63 sorts cholesterol into endosomes for storage and distribution via exosomes’: Many congratulations to Dr. Roberta Palmulli on her recent Nature Cell Biology publication, providing novel insights into cholesterol trafficking to exosomes. Read more…

June 2024


  • Departmental Centenary: A wonderful time celebrating the 100th anniversary of the Department of Biochemistry at Cambridge. Congratulations to PhD student Osian Jones on receiving a prize in the Centenary Photography Competition for his confocal image, ‘Mitochondrial Transfer Between Pancreatic Cancer Cells via Tumour Microtubes.’

May 2024


  • ‘CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake’: New eLife publication implicating CYRI-B as a Novel Mediator of Pancreatic Cancer Metastasis. Read more…

May 2024


  • 2024 Vice-Chancellor’s Social Impact Award: Congratulations to Machesky Lab PhD student Sam Hodder for winning this award for the development of ‘Chum’, an interactive platform using stories and games to educate children with cancer about their treatments.

May 2024